OxyFile #617

Does ozone therapy normalize the cellular redox balance? 
Implications for therapy of human immunodeficiency virus infection 
and several other diseases. 

Bocci V 

Institute of General Physiology; University of Siena, Italy. 

Med Hypotheses, 1996 Feb, 46:2, 150-4 


The role of ozone on earth is controversial, as in the 
stratosphere it is protective against excessive ultra violet 
irradiation, and in the troposphere it is toxic for animals and 
plants. The effectiveness of ozone against pathogens is well 
recognized and ozone appears to be the best agent for 
sterilization of water. In spite of this, the use of ozone in 
medicine has been overlooked or despised, mostly because it has 
been either misused or used without appropriate controls. Studies 
carried out in our laboratory have revealed that ozone can display 
relevant biological effects and that, having defined its 
therapeutic index, can become an important and reliable drug for 
the treatment of several diseases. An exciting new aspect is that 
ozone, being a strong oxidizer, can stimulate the increase of 
cellular anti-oxidant enzymes, eventually inhibiting the oxidative