The efficacy of using ozone preparations in the combined treatment of paranasal sinusitis Petrov GM; Kudriavtsev BP; Akulich II Voen Med Zh, 1996 Dec, 317:12, 26-8, 80 Abstract In controllable study efficiency of application of ozone preparations in 39 patients with acute and chronic purulent maxillary polysinusitis was studied. Purulent maxillary sinusitis, which in 44% was combined with frontitis and in 56%--with fronto- ethmoiditis was diagnosed in all patients. Besides traditional therapy all patients were washed out daily inflamed sinuses with 0.9% solution of sodium chloride, saturated of ozone. After washing out the sinuses were aerated during 15-20 minutes through paracentesis needles and catheters with ozone-oxygen mixture, containing 6 mg/l of ozone. Speed of mixture flow--1 1/min. To the half of patient with phenomena of intoxication were introduced I/V 400 ml of physiologic salt solution (ozone concentration--0.8 mg/l). Treatment rate is 3-6 infusions. In patients pyorrhea and allocation of bacteria stopped 2-3 days earlier, than in control group, level of molecules of average weight was faster reduced to norm in the plasma of blood. Reduction of concentration of molecules of average weight corresponded to essential improvement of patient clinical condition (P < 0.01). Experience of ozone application testified about its high efficiency in paranasal sinusitis treatment.