OxyFile #595

Ozonetherapy in Dermatoses: 1.5 Year Out-Patient Practice

S.L. Krivatkin et al.
Sormovo Interdistrict Dermatoveneriological Dispensary
Nizhny Novgorod, Russia

Out-patient ozonetherapy (OT) was applied to 292 patients suffering 
from different forms of acne and rosacae - like dermatitis (51), 
alopecia (15), drug eruptions (3), epidermophytosis pedis (11), 
eczema (46), herpes (65), lichen ruber planus (3), neurodermitis 
(21), prurigo (2), psoriasis (26) and arthritis (2), pyoderma (37), 
scleroderma (4) and venous leg ulcers (6).  Five standard forms of OT 
were used: autohemotherapy minor, intramuscular injections, 
techniques with the use of plastic bag, ozonized oil and water.  As a 
source of O2/O3 mixture the home ozonizer was used (concentration of 
O3 - 7-20 mcg/ml).  Laboratory control of the treatment was realized 
by means of available bacteriological, biochemical, clinical, 
immunological and roentgenological examinations.  Summing up the 
nearest therapeutical results of OT it can be said that OT is high 
effective in herpes, most forms of pyoderma, acute eczema and 
epidermophitosis pedis; effective in neurodermitis, acne, 
scleroderma, venous leg ulcers; promising results were obtained in 
alopecia, psoriatic arthritis and drug eruptions.  Follow-up 
investigations were also carried out: in most cases OT ensured long 
or longer than previous traditional treatment remissions.  The 
efficacy of OT was compared with the effectiveness of control 
treatment (routine autohemotherapy in herpes, traditional therapy in 
acne): the advantage of OT was shown.  As a rule, OT was well 
tolerated with the exception of a few complaints on painful 
injections and light dizziness just after the treatment.  Only one 
woman suffering from hydradenitis and diabetes supposedly had an 
allergic reaction in the form of allergic dermatitis after forth and 
then fifth treatment.  Taking into consideration the efficacy, 
safety, simplicity, and cheapness of OT we believe that it is worth 
to be used in out-patient dermatological practice.

Publish Date: 1994