OxyFile #519

Biochemical and Biophysiological Actions of Ozone

By Tom Harrelson

Reprinted with Permission

Ozone functions as a antiseptic, disinfectant, deodorant, 
bactericide, virucide, fungicide, paraciticide, protozoacide, 
hemostat, analgesic, circulatory stimulant, wound cleansing agent, 
and wound healing agent.  Ozone performs these functions through 
ionization, subatomic exchange (oxidation), electron/free radical 
reactions, electrovoltaic stimulus, and electromagnetic reactions 
resulting in profuse photon and energy transfer.  Among the 
numerous actions of OZONE are the following:

1.  Accelerates glycolysis (breakdown of glycogen) in RBCs, thus 
    a. Increases the release of O2 from the hemoglobin in the 
       blood to the tissues.
    b. Enhances formation of Acetyl Coenzyme-A, which is vital in 
       metabolic detoxification.
    c. Influences the mitochrondrial transport system, thus 
       enhancing the metabolism of all cells and safeguarding 
       against mutagenic changes.
    d. Increases red blood cell pliability. blood fluidity, and 
       arterial PO2 (oxygen content) and decreases rouleaux 
       clumping, which interferes with the normal functioning of 
       the red blood cell metabloism.

2.  Reduces NAPH production and oxidizes cytochromes.

3.  Stimulates the reticulo-endothelial system, thus rebuilding 

4.  Chelates Iron and Calcium, thereby blocking the formation of 
    "free radicals".

5.  Increases ATP production, thus allowing for the production of 

6.  Activates the enzymes involved in peroxide or oxygen "free 
    radical" destruction (i.e.- Glutathione, Catalase, and 

7.  Disrupts the lipid cell membranes of anerobic and/or partially 
    anerobic pathogenic organisms, plus weak and/or defective 
    cells only by atomic disassociation and solubilization (lipid 
    peroxidation) due to the action of the hydroxyperoxides 
    formed, thereby exposing and destroying them.

8.  Increases leukocytosis (production of the white blood cells) 
    and phagocytosis (an action whereby certain white blood cells 
    destroy foreign matter.

9.  Stimulates the production of INTERFERON and INTERLEUKIN-II.

10. Opens the circular plasmid DNA, which lessens bacterial 


OZONE-The Breath of Life, Robert Willner, M.D., The Family News, 
Vol. V No. I.

Polyatomic Oxygen, Basil Wainwright, Ph.D., The Family News, Vol. 
V No. II.

Medical Ozone (O3) Therapy, Stanley Beyrle, M.D., HIV Treatment 
News, Report No. 6.

Ozone in Medicine, Gerard V. Sunnen, M.D., Journal of Advancement 
in Medicine, Vol I, No. 3, Fall 1988.

The Use of Ozone in Medicine, Siegfried Rilling, M.D. & Renate 
Viebahn, Ph.D., Karl F. Haug, Heidelberg.

OZONE Fact Sheet No. 4-Med.>11/96