Application of Ozonized Oil in the Treatment of Alveolitis O. Cruz, S. Menéndez(1), M. E. Martínez(2), T. Clavera(2). "Elpidio Berovides" Educational Polyclinic Center, Cuba. 1 - Ozone Research Center, Cuba. 2 - Siboney Stomatological Clinic, Cuba. Septical alveolitis or septical osteitis of the alveolar cavity, after extraction is the most frequent and painful complication of exodontia. It can developed, at the third or fourth post surgical day and it is characterized by a deep pain and necrotic odor. The etiology of the alveolitis is unknown, but the following facts increase its incidence: traumatisms, infections, vascular supply decrease in the surrounding bone and general systemic conditions. The etiology can be related to an inappropriate nutrition of the clot formed in the alveolus. Thanks to the germicide action of OLEOZON, just as its oxygenant power, that favors the tissue regeneration, this ozonized oil was applied in the treatment of alveolitis. 100 adult patients, divided at random, in two groups of 50 patients, were studied. To all patients, before treatments, saline solution for removing all rest of necrotic clot and/or inappropriate contents, was gently irrigated into the alveolar cavity and carefully dried with sterile swabs. Experimental group was covered, daily, with OLEOZON. Control group was treated locally with Alvogil, also daily, in addition to oral antibiotics. Cured was made every 72 hours and as many medical inspection as they need. Healing criterion was done, taking into account, the formation of cicatrization tissue and pain relief. Diabetes Mellitus and traumatic extractions were the factors that more favor the alveolitis appearance. In patients treated with OLEOZON and Alvogil, 92 % and 58 % of cured patients, respectively, were achieved, in 2 or 3 visits, with statistical significant differences between them. In OLEOZON group, 8 % needed 4 to 6 visits in order to complete their treatment and with Alvogil the number of patients represented 42 % Patients treated with OLEOZON cured faster than the patients treated with Alvogil with statistical significant differences. OLEOZON was well tolerated by patients, without any side effect. OLEOZON can be considered as an effective medication in the alveolitis treatment. Source: 2nd International Symposium on Ozone Applications Havana, Cuba - Mach 24-26, 1997.