Experiences with Ozone Therapy in the Sutton Disease (Periadenitis Mucous Necrotica Recurrens). A Case Report G. Legrá, J. Turrent(1), S. Menéndez(1), M. del C. Luis(2). Playa Dental Clinic, Cuba. 1 - Ozone Research Center, Cuba. 2 - William Soler Pediatric Hospital, Cuba. Sutton disease (Periadenitis Mucous Necrotic Recurrent) is a rather rare pathological condition characterized by several ulceration of the mouth, very painful, to a tendency to relapse and with a retracted healing. Many factors are involucrated in the pathogenesis of this disease, but the immgical response is one of the main aspects considered in the evolution of the pathological process. It is presented a case of a 12-year-old age patient with diagnosis of Sutton disease with 5 years of evolution, without satisfactory results, after testing multiple therapeutic methods. The patient has been treated with ozone therapy by gas rectal insufflation (20 sessions) and local applications of ozonized sunflower oil (OLEOZON) during 2 years. Relapses decrease during the treatment and the healing of the ulcerous injuries was more rapid and scar retractions was not observed. It is made a wide review of the topic in order to justify the application of this therapeutic method. This is the first report using ozone therapy treatment in this disease. Source: 2nd International Symposium on Ozone Applications Havana, Cuba - Mach 24-26, 1997.