OxyFile #471

Correlation of Plasma Interleukin 1 Levels with Disease Activity 
in Rheumatoid Arthritis with and without Ozone

Z. Fahmy.

Augusta-Klinik, 55543 Bad Kreuznach, Germany.

The mean plasma level of interleukin 1 beta was significantly 
higher in 51 patients with rheumatoid arthritis  (RA) than in 21 
rheumatoid arthritis patients treated with ozone, as control group 
of similar age in both groups. Plasma IL-1 beta correlated 
positively with Ritchie joint index, pain score, and erythrocyte 
sedimentation rate and correlated negatively with haemoglobin 
concentration. These results support the idea that IL-1 beta has a 
central role in the phatogenesis of RA and the ozone has 
influenced in the concentration level of  IL-1 beta.

Source: 2nd International Symposium on Ozone Applications
        Havana, Cuba - Mach 24-26, 1997.