OxyFile #390

This article is apart of a series. Please read the preface (oxy00362) for more details.

Authority:  John F. Kessel, M.D., Donald K. Allison, M.D.
            Martha Kaime, Maria Quiros, Albert Glockner
Department of Bacteriology and Parasitology School of Medicine,
University Southern California


Subject:  OZONE THERAPY - for Cysts of Endamoeba Histolytica

Ozone has been known for years to be a highly effective oxidizing
agent.  It has been used extensively in Europe.

While certain of the early work with Ozone indicates its
bactericidal properties, few quantitative tests have been
reported, and WITH THE EXCEPTION OF STUDIES IN THIS LABORATORY no
records are known to the author which compare the bactericidal
effects of CHLORINE AND OZONE nor the effects of chlorine and
Ozone on protozoan cysts or viruses.

A comparison of the cysticidal and bactericidal effects of
chlorine and Ozone is made at pH levels ranging from 5 to 9.  One
hundred cysts per cc. were selected as a standard dosage for the
experiments, the bacterial count accompanying this dosage ranging
between 500,000 and 1,000,000 per cc. chlorine residuals of 0.5 to
1.0 p.p.m. were compared with Ozone residual of only 0.3 p.p.m. at
time intervals ranging from two to 240 minutes at temperature of
27 C.

The bactericidal and cysticidal times required by OZONE producing
a residual of only 0.3 p.p.m. were SEVERAL TIMES LESS THAN THOSE
required by chlorine producing residuals of 1.0 p.p.m.

Thus, in both bactericidal and cysticidal studies Ozone was
several times more effective than either H. T. H. or gaseous
chlorine.


In "American Journal of Tropical Medicine"