OxyFile #368

This article is apart of a series. Please read the preface (oxy00362) for more details.

Authority: Hans Kleinmann. M.D.,

Subject: OZONE - for treatment of diseased bodily cavities.

General information concerning new possibilities of using gases in

"Whereas, thus far in medicine the use of pharmaco was limited to
the use of a solid or liquid state of aggregation, and the use of
gas with limited exceptions, priorily was used for diagnostics and
mechanical purposes, this work aims to point out what advantages
and multifarious possibilities extended employment of gases with
pharmacological qualities could offer."

I have come to the conclusion that in treatment of infected or
general diseased bodily cavities and passages, gases of
pharmacological qualities offer absolute advantages.

All infections of bodily cavities, which have not been treated
locally thus far (Pleur, Peritoneum, Pelvis Renalis) or have been
treated with liquid disinfectors (Bladder, urethra, intestines)
would be accessible with such gaseous treatments, and considering
the effectiveness of the remedy, one must give primarily
superiority to the gaseous state of aggregation.

Only imagine how exceptionally deep folded and how richly wrinkled
a mucous membrane of the bladder is, or how much protection
bacteria finds in glandular openings or passages in the urethra:
therefore, it is quite clear that a liquid solution which is
rinsing the surface only, can have no deeper penetrative effects.    
It is different with gas.  The same will stretch out the folds and
penetrate into the wrinkles and passages.

Considering all the mentioned conditions, from all known gases, it
seems that Ozone is the one that can perform it.  It is composed
of three atoms of oxygen, and has the tendency to split off one of
the atoms of oxygen.  In so doing, it is a super-oxidizing agent,
leaving as a by-product oxygen only, and this can be harmlessly
absorbed by the tissue.  This fact has persuaded me more than
anything else for my first experimental investigation to use Ozone
instead of light solutions of ether, chloroform, halogen, which as
a by-product delivers corrosive hydro-acids.

In "Treatment with Pharmacologically-active Gases",  "The Action
of Ozone"