The following is the final part to a paper written by Dr. Sunnners "Dr. Sunnen's Paper on Historical and Current Ozone Usage". How this helps your research. If you know of any source of Oxygen Therapies or Products, please let me know. Trying to compile a comprehensive list. Historical and Current Ozone Usage - Part II Today, we continue on the history and current usages of Ozone, I am writing excerpts from the book "Oxygen Therapies", by Ed McCabe on "Dr. Sunnen's Paper on Historical and Current Ozone Usage", pp 100-102: Intravenous Treatment: Now rarely used, this method of direct injection (without first mixing the blood with ozone outside the body), was used by Lacoste in 1951 on gangrene. It is rarely used because of the potential of accidents due to too rapid an injection. He found that up to 10 ml of pure ozone/oxygen could be directly injected into the leg artery, or a vein, without getting dangerous bubbles in the blood, since both gases are readily soluble in blood. Muscular Injection: Used with blood treatment, this is an added cancer therapy. Up to 10 ml of the pure mixture is injected into the muscles. Ozonated Water: Ozone is about 10 times more soluble in water than oxygen. Used mostly in dental surgery, it improves the local oxygen supply, and inhibits bacteria. Ozone water has also been used on peridontal disease, swallowed for treatment of gastric cancer, and applied as a wash in intestinal or bladder inflammation. Ozone Ointments: Mixed with olive oil, this mixture gives a low strength, long term dose of ozone and lipid peroxidases to the tissues. Used on fungal growths and skin ulcers. Ozone Baths: Ozone bubled through warm water irrigates the skin, to disinfect and treat eczema and skin ulcers. Blood Purification: An exciting possibility, all the world's blood supplies may possibly be made viral free! Treating 500 ml of whole blood with 100 ml of ozone/oxygen mixture (40-50 ug/ml) is reported to render it virus free without injuring any healthy cells. One particular study tested ten thousand treated samples and found no hepatitis. In the future, this technique may also be used in removing the AIDS virus. One preliminary unpublished study indicates this to be so. Effects of Ozone: Most studies, up to this point, have only focused on proving how breathing ozone was toxic, or name it as air pollution. Pure ozone, applied in the proper say, is quite a different story. The studies where animals have inhaled it do not equal the response of the human lungs, because there are so many differences in the anatomy and physiology. Mice have the most trouble with it, and birds the least. Inhaling very low dosages increases enzyme activity, while overdosage can result in bleeding in the lungs. We see again the window concept, and refer you to what "Merlin" found out. Due to the danger of breathing in too much ozone, modern treatment machines are designed to prevent any leakage into the treatment room, as well as catalytically converting excess ozone to oxygen during administration. some studies, however, point to beneficial effect of low dosage ambient ozone. Bactericical, Virucidal, and Fungicidal Action: We have known ozone kills and inhibits pathogens since the nineteenth century. What we haven't done is the tests proving exactly why it has these effects. Only a few microgreams per liter provide germ killing action. It works even faster on viruses than bacteria, at lower dosages, and is influenced by pH, temperature, and other nearby organic compounds. Different viruses have different susceptibility to destruction by ozone, for example, the polio virus is forty times more resistant than other viruses. Ozone's popular reputation as a bactericide centers on it's ability to destroy the pathogen's outer fatty/protein shell. In one study it actually penetrated the cell's membrane and changed the DNA. Higher organisms have enzymes that can restabilize disrupted DNA & RNA, where lower forms do not. This could be why ozonem, at proper levels, will kill a virus (a lower lifeform), and leave a person's (higher lifeform) cells unharmed. One study showed the ability to destroy candida fungi to be dependent on their stage of growth. Budding cells were the most sensitive. Another study showed a low dose increasing the growth of two other fungi. Viruses are genetic parasites, and can be separated inito families, based on structure. Those containing lipids are the most sensitive: herpes, mumps, measles, flu, rabies, HIV/AIDS. In some, the shell is damaged, in others they remain whole, but unable to reproduce. Often the ozone is used up in a blood reaction, and the products of that reaction cause the destruction or inactivation of the pathogens. Although unlikely to be outright curative by itself, when combined with other therapies, ozone may lessen clinical severity or duration. Two Good Medical Ozone Books: "Ozone in Medical Therapy", by Julius LaRaus; $80.00, from: International Ozone Association; 83 Oakwood Ave.; Norwalk, CT 06850 "The Use of Ozone in Medicine, A Practical Handbook and Reference Guide", by Siegfried Rilling, MD. Price unknown. Check address above. I believe that every home library should have Ed McCabes - "Oxygen Therapies". Ask your health food store.