OxyFile #299

Influence of Ozone Therapy in Rheumatoid Arthritis

Ziad Fahmy
Chief Physician, Augusta Klinik
6550 Bad Kreuznach, F.R.G.


The treatment of patients with rheumatoid arthritis is a challenge 
for rheumatologists.

Several clinical studies have shown that anti-malarial agents, gold 
salts, Methotrexat, and some cytotoxic agents have disease-modifying 
properties, but response to treatment with these drugs is variable 
and a certain proportion of the RA patients do not benefit.

O3/O2 has a potent immunomodulator capable of selective modulation of 
subpopulations of immunocompetent cells.

This properties suggested that ozone useful of treatment of RA.

Clinical efficacy was observed one month after the beginning of 
treatment, was well established after many months of therapy, and 
remained stable for the remainder of the one-year treatment period.

It is known that ozone administration in different applications forms 
for the time between 6 to 8 weeks cause improvement of the general 
condition of the patients (clinically and biochemically).

Concluded that ozone id clinically effective for the treatment of 
patients with refractory RA, but its value for intervention therapy 
is limited.

Publish Date: 1991