OxyFile #194

UI  - 91059292
AU  - Vaughn JM
AU  - Chen YS
AU  - Novotny JF
AU  - Strout D
TI  - Effects of ozone treatment on the infectivity of hepatitis A
AD  - Department of Microbiology, University of New England College of
      Medicine, Biddeford, ME 04005.
AB  - The inactivation of a large-focus-forming variant of hepatitis A
      virus (HM-175) by ozone was investigated. Experiments using
      mainly single-particle virus preparations suspended in
      phosphate-carbonate buffer were conducted over a range of pH
      levels (6-8) at 4 degrees C. Viral enumerations involved the use
      of a radioimmunofocus assay. While some tolerance to lower (i.e.,
      0.1-0.5 mg/L) ozone residuals was noted, the exposure of virus
      particles to ozone concentrations of 1 mg/L or greater at all pH
      levels resulted in their complete (5 log) inactivation within 60
      s. The pH-related effects that were observed were not considered
      to be significant.
LA  - Eng
SO  - Can J Microbiol 1990 Aug;36(8):557-60