Acute oxygen therapy. RM Leach & NT Bateman British Journal of Hospital Medicine, 1993 May 5-18, 49(9):637-44. (UI: 93284336) Abstract: Tissues require oxygen for survival. Its delivery depends on adequate ventilation, gas exchange and distribution in the circulation. Many causes of hypoxaemia can be corrected by adding oxygen to the inspired air but response is variable and must be measured.