TI: Effect of Endovenous Ozone Therapy on Lipid Pattern and Antioxidative Response of Ischemia Cardiopathy Patients DT: Not Known AU: Frank Hernandez, Silvia Menendez and Rolando Wong SO: National Center for Scientific Research, Havana, Cuba. Medical and Surgical Research Center. AB: Patients with cardiac infarction have shown a decrease upon gluthathione peroxidase and superoxide dismutase activities, which are beginners in the scavenger processes of lipid peroxide and superoxide radical respectively. In the present study, the effects of a specific scheme of endovenous ozone therapy on serum lipid pattern and on antioxidant defense system, gluthathione redox system specifically, was investigated in the blood of patients with myocardial infarct. Twenty-two patients who had an infarction, between one year and three months before the study were treated with ozone by major autohemotherapy during fifteen sessions. A statistical significance decrease in total cholesterol and low density lipoprotein were observed. No statistical significance increase on gluthione peroxidase and glucose 6-phosphate dehidrogenase activities were found. In the case of glucose 6-phosphate dehidrogenase activity, it was increased significantly at 5th session of treatment. No change in lipid peroxidation level was observed. It was concluded that endovenous ozone therapy in patients with myocardial infarction has a beneficial effect on serum lipid metabolism and provoking the activation of antioxidant protection system.