OxyFile #81

TI:  Immunological Effect of Ozone (O3/O2) in Rheumatic Diseases

DT:  Not Known

AU:  Z. Fahmy

SO:  Augusta-Klinik, 6550 Bad Kreuznach, Germany

AB:  The therapeutical application of ozone has proven its value 
     in compensated autoimmune diseases as a support of 
     immunsuppressiva therapy.  Through ozone therapy, a rapid 
     and effective elimination of pathological macro-molecules 
     and mediators is attained.

     Ozone and its popularity undoubtedly stems from the fact 
     that it is less toxic than most other immunosuppressiva 
     agents, rather than from is less efficacy.

     In the absense of any convincing evidence to the contrary, 
     out clinical impression is that ozone is moderately 
     effective in treating severe rheumatoid arthritis and is 
     decreasing steroid requirements.

     The positive effect of ozone therapy in rheumatoid arthritis 
     does not remain clear as long as the pathogenesis of the 
     disease remains unknown.