TI: Ozonotherapy Efficiency in the Treatment of Patients with Atherosclerosis of Coronary and Cerebral Vessels DT: Not Known AU: Natalia I. Zhulina, Claudia N. Kontorschikova, Natalia V. Morozova SO: Centre of Ozonotherapy, Medical Institute, Nizhny Novgorod, Russia. AB: The effect of ozonized isotonic solution of sodium chloride in the treatment of ischemic patients with the clinic of stenocardia - 11,111 and cerebrovascular insufficiency due to atherosclerosis was studied. By the end of the treatment course, the frequency of angina attacks was reduced 2,5 time, decreasing nitroglycerin dosage and increasing tolerance to physical loads. Some patients revealed positive ECG dynamics, i.e. normalization of repolarization processes. Organic neurological symptoms were not changed. Vegetal disfunction symptoms improved. REG data demonstrated positive dynamics, dicrease of vessel wall reactivity. EEG showed alfa-rhythm activation. Among psychological parameters emotional tense and alarm manifestation were logically decreased, general condition being improved. No complications or any negative reactions to ozonotherapy were registered. Biochemical tests revealed intensification of antioxidant protective system decrease in levels of molecular lipid peroxidation products: conjugated dienes and Shiff's bases; normalization of the following data of lipid change: cholesterol and triglycerides. Thus ozonotherapy application in chronic insufficiency of coronary and cerebral vessels makes up a new trend in prophylaxis and rehabilitation of this category of patients.