OxyFile #55

TI:  Immunological Examinations in Patients with Chronic 
     Conditions Under Administration of Ozone/Oxygen Mixtures

DT:  July 1989

AU:  J. Washuttl, R. Viebahn and I. Steiner

SO:  Ozone Science & Engineering Vol. II, pp. 411-417

AB:  In four groups of patients with chronic conditions receiving 
     an ozone application (intravascular administration of 
     ozone/oxygen mixtures with or without autohemotherapy), the 
     immunoglobulins IgA, IgG and IgM were determined in serum; 
     in groups 1 and 2, lysozyme and vitamin A values also were 
     measured.  The groups were broken down as follows:

     Group 1:  19 patients with carcinoma of the cervix.  Group 
     2: 20 patients with carcinoma of the ovaries.  Group 3: 
     patients with chronic conditions (80% patients with 
     rheumatoid arthritis), short-term study (34 patients).  
     Group 4: patients with chronic conditions (80% patients with 
     rheumatoid arthritis), long-term study (47 patients).  A 
     further breakdown into statistical categories in groups 1 
     and 2 showed no significant changes in the immunoglobulins 
     examined, including the vitamin A and lysozyme values.

     A short-term influence in group 3 became evident through a 
     significant increase in immunoglobulin G, whereas no 
     significant decrease was observed in all immunoglobulins in 
     group 4.  An immunosuppressive effect of the ozone applied 
     could not be detected in any of the 4 groups.