OxyFile #14

Does ozone therapy normalize the cellular redox balance? 

Implications for therapy of human immunodeficiency virus infection 

and several other diseases. 

Author:  Bocci_V 

Address: Institute of General Physiology; University of Siena, 


Source:  Med Hypotheses, 1996 Feb, 46:2, 150-4 


The role of ozone on earth is controversial, as in the 

stratosphere it is protective against excessive ultra violet 

irradiation, and in the troposphere it is toxic for animals and 

plants. The effectiveness of ozone against pathogens is well 

recognized and ozone appears to be the best agent for 

sterilization of water. In spite of this, the use of ozone in 

medicine has been overlooked or despised, mostly because it has 

been either misused or used without appropriate controls. Studies 

carried out in our laboratory have revealed that ozone can display 

relevant biological effects and that, having defined its 

therapeutic index, can become an important and reliable drug for 

the treatment of several diseases. An exciting new aspect is that 

ozone, being a strong oxidizer, can stimulate the increase of 

cellular anti-oxidant enzymes, eventually inhibiting the oxidative